Brachytherapy, SABR / SBRT, SRS, and Stereotactic Radio surgery Brachytherapy, SABR / SBRT, SRS, and Stereotactic Radio surgery


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Brachytherapy, SABR / SBRT, SRSa and Stereotactic Radio surgery

Treating cancer from the inside

Varian Brachytherapy has proven to be a successful treatment for cancers of the prostate, cervix, endometrium, breast, skin, bronchus, esophagus, and head and neck, as well as soft tissue sarcomas and several other types of cancer. Brachytherapy treats cancer by placing radioactive sources directly into or next to the area requiring treatment. This enables clinicians to deliver a high dose with minimal impact on surrounding healthy tissues.

Brachytherapy primarily uses two different techniques:

Low Dose Rate (LDR) uses a lower strength radioactive source and is associated with longer treatment times (for the one time treatment). The most commonly used LDR treatment site is the prostate which involves permanent placement of tiny radioactive seeds in tissue in the prostate. Historically LDR has been used in the treatment of other sites such as gyn and head & neck where low activity sources are temporarily placed for several days & then removed.

High Dose Rate (HDR) uses a higher strength radioactive source contained within an afterloader device. The afterloader delivers the source for a brief period of time to catheters, needles, or other appliances placed in the tumor site. Per treatment, HDR is much shorter procedure (minutes vs. days) than LDR but it does require multiple treatments. Increasingly more common, HDR techniques have replaced LDR techniques for most body sites.

With any radiotherapy technique, the goal is the same: to conform the dose to the size and shape of the target while limiting side effects by sparing the surrounding healthy anatomy. In brachytherapy, radiation falls off very rapidly from the target area easily accomplishing this objective.

The oldest form of radiotherapy, brachytherapy now uses the latest in computer and radioactive source technology. Image guided brachytherapy (IGBT) combines advanced imaging techniques with advanced brachytherapy procedures allowing doctors to treat patients quickly and precisely.

Active in the brachytherapy market since 1994, Varian produces a full range of brachytherapy products including afterloaders, applicators, and treatment planning software.




Stereotactic Ablative Radiotherapy / Stereotactic Body Radiation Therapy

Stereotactic Ablative Radiotherapy (SABR) or Stereotactic Body Radiation Therapy (SBRT) is emerging as an attractive option for treating cancers in the lung, head and neck, prostate, liver and other disease cites outside the CNS. SABR / SBRT is a non-invasive treatment procedure similar to SRS, except that it deals with tumors outside the central nervous system (CNS).

The objective of SABR / SBRT is to escalate the dose to the target lesion and thus to increase local control while limiting dose to nearby critical structures and normal tissue. Some requirements of SABR / SBRT program may include precise localization of the target lesion in the treatment planning process; account for tumor motion due to respiration or other changes in the body; highly conformal dose distribution to the target volume including a steep dose gradient to minimize dose to surrounding healthy tissue sparing; and image-guidance at the time of dose delivery for verification and adjustment of the target localization.

Designed to treat targets using sub millimeter mechanical accuracy of the couch, collimator, and gantry, Varian’s linear accelerators dynamically synchronize imaging, patient positioning, motion management and treatment delivery. These versatile, high-performance treatment devices—including the

Trilogy linear accelerators—can be used for many forms of radiation therapy modalities.



SRS- Stereotactic Radio surgery

Radiosurgery can be the treatment of choice for certain cancers. Stereotactic radiosurgery (SRS) delivers high doses of radiation to treat tumors with great precision. SRS is a technique that is most commonly used for tumors or other medical conditions in the brain or central nervous system (CNS). With SRS, clinicians can focus the radiation dose to the outline of the tumor and minimize dose to the surrounding healthy tissue. SRS treatments use high precision, accuracy, and sophisticated 3-D imaging to deliver a concentrated dose of radiation in a single treatment. In some cases fractionated stereotactic radiosurgery is used. This is a process in which the total dose of stereotactic radiation is divided into several smaller doses of radiation on separate days of treatment ranging from two to five treatments.

Radiosurgery treatments using Varian technology are helping expand the options available to multidisciplinary oncology teams worldwide. The Varian Edge radiosurgery system is a dedicated, end-to-end clinical turnkey solution for radiosurgery treatments. The technological components have been specifically designed and chosen to ensure that the SRS requirements of a clinic are met. With the power, precision and speed found throughout this system, the Edge enables clinicians to navigate the intricacies of cancer care with confidence.